G32A (p.Gly32Ala) variant of CALR (Calreticulin)
G32A (p.Gly32Ala) in CALR (Calreticulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
G32A (p.Gly32Ala) variant details
- p.Gly32Ala
- ESP rs140472880
- ExAC rs140472880
- TOPMed rs140472880
- gnomAD rs140472880
- Missense
- Variant Prioritization Score for Impact Estimate 0.309
- REVEL 0.01
- CADD 17.20
- PolyPhen-2 0.01
- SIFT 0.23
- Most common in the African/African-American population (allele frequency 7.2e-05)
- Structural context available