D71G (p.Asp71Gly) variant of CALR (Calreticulin)
D71G (p.Asp71Gly) in CALR (Calreticulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data and structural context.
D71G (p.Asp71Gly) variant details
- p.Asp71Gly
- gnomAD rs1404498335
- Missense
- Variant Prioritization Score for Impact Estimate 0.58
- REVEL 0.53
- CADD 29.50
- PolyPhen-2 0.21
- SIFT 0.03
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available