D59N (p.Asp59Asn) variant of CALR (Calreticulin)
D59N (p.Asp59Asn) in CALR (Calreticulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data and structural context.
D59N (p.Asp59Asn) variant details
- p.Asp59Asn
- ExAC rs780108025
- TOPMed rs780108025
- gnomAD rs780108025
- Missense
- Variant Prioritization Score for Impact Estimate 0.535
- REVEL 0.43
- CADD 29.60
- PolyPhen-2 0.07
- SIFT 0.04
- Most common in the REMAINING population (allele frequency 5e-05)
- Structural context available