G99V (p.Gly99Val) variant of CALM3 (Calmodulin-3)
G99V (p.Gly99Val) in CALM3 (Calmodulin-3) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.85 / 1. The record also includes population frequency data and structural context.
G99V (p.Gly99Val) variant details
- p.Gly99Val
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.846
- REVEL 0.86
- MetaLR 0.86
- MetaSVM 1.01
- CADD 29.80
- PolyPhen-2 0.97
- SIFT 0.00
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available