E15D (p.Glu15Asp) variant of CALM3 (Calmodulin-3)
E15D (p.Glu15Asp) in CALM3 (Calmodulin-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data and structural context.
E15D (p.Glu15Asp) variant details
- p.Glu15Asp
- TOPMed rs1366326090
- gnomAD rs1366326090
- Missense
- Variant Prioritization Score for Impact Estimate 0.525
- REVEL 0.52
- MetaLR 0.70
- MetaSVM 0.29
- CADD 22.10
- PolyPhen-2 0.12
- SIFT 0.06
- Most common in the Ashkenazi Jewish population (allele frequency 0.00029)
- Structural context available