R91C (p.Arg91Cys) variant of CALM1 (Calmodulin-1)
R91C (p.Arg91Cys) in CALM1 (Calmodulin-1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.70 / 1. The record also includes population frequency data and structural context.
R91C (p.Arg91Cys) variant details
- p.Arg91Cys
- cosmic curated COSV99700
- Ensembl rs1687185440
- cosmic curated COSV52194
- Missense
- Variant Prioritization Score for Impact Estimate 0.702
- REVEL 0.66
- MetaLR 0.74
- MetaSVM 0.58
- CADD 24.50
- PolyPhen-2 0.18
- SIFT 0.02
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available