S98T (p.Ser98Thr) variant of CALCRL (Q16602)
S98T (p.Ser98Thr) in CALCRL (Q16602) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
S98T (p.Ser98Thr) variant details
- p.Ser98Thr
- rs374525357
- cosmic curated COSV10113
- ESP rs374525357
- gnomAD rs374525357
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.176
- REVEL 0.06
- CADD 17.90
- PolyPhen-2 0.01
- SIFT 0.78
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available