S98L (p.Ser98Leu) variant of CALCRL (Q16602)
S98L (p.Ser98Leu) in CALCRL (Q16602) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
S98L (p.Ser98Leu) variant details
- p.Ser98Leu
- TOPMed rs199799965
- gnomAD rs199799965
- Missense
- Variant Prioritization Score for Impact Estimate 0.412
- REVEL 0.11
- CADD 33.00
- PolyPhen-2 0.51
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available