M53T (p.Met53Thr) variant of CALCRL (Q16602)
M53T (p.Met53Thr) in CALCRL (Q16602) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
M53T (p.Met53Thr) variant details
- p.Met53Thr
- TOPMed rs936879860
- Missense
- Variant Prioritization Score for Impact Estimate 0.285
- REVEL 0.14
- CADD 19.30
- PolyPhen-2 0.01
- SIFT 0.63
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available