L34F (p.Leu34Phe) variant of CALCRL (Q16602)
L34F (p.Leu34Phe) in CALCRL (Q16602) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
L34F (p.Leu34Phe) variant details
- p.Leu34Phe
- cosmic curated COSV10113
- Missense
- Variant Prioritization Score for Impact Estimate 0.297
- REVEL 0.10
- CADD 7.80
- PolyPhen-2 0.00
- SIFT 0.24
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available