G81E (p.Gly81Glu) variant of CALCRL (Q16602)
G81E (p.Gly81Glu) in CALCRL (Q16602) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.81 / 1. The record also includes population frequency data and structural context.
G81E (p.Gly81Glu) variant details
- p.Gly81Glu
- ExAC rs761630558
- gnomAD rs761630558
- Missense
- Variant Prioritization Score for Impact Estimate 0.808
- REVEL 0.83
- CADD 25.30
- PolyPhen-2 0.79
- SIFT 0.02
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available