D77Y (p.Asp77Tyr) variant of CALCRL (Q16602)
D77Y (p.Asp77Tyr) in CALCRL (Q16602) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
D77Y (p.Asp77Tyr) variant details
- p.Asp77Tyr
- TOPMed rs1273852056
- gnomAD rs1273852056
- Missense
- Variant Prioritization Score for Impact Estimate 0.394
- REVEL 0.25
- CADD 23.30
- PolyPhen-2 0.50
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available