G21W (p.Gly21Trp) variant of CACNA1C (Q13936)
G21W (p.Gly21Trp) in CACNA1C (Q13936) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes population frequency data, published literature, and structural context.
G21W (p.Gly21Trp) variant details
- p.Gly21Trp
- rs2154136802
- gnomAD 12-2115235-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.629
- REVEL 0.52
- CADD 27.90
- PolyPhen-2 0.62
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available