T77N (p.Thr77Asn) variant of C3 (Complement C3)
T77N (p.Thr77Asn) in C3 (Complement C3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
T77N (p.Thr77Asn) variant details
- p.Thr77Asn
- TOPMed rs1968115872
- gnomAD rs1968115872
- Missense
- Variant Prioritization Score for Impact Estimate 0.21
- REVEL 0.19
- CADD 1.58
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available