T4N (p.Thr4Asn) variant of C3 (Complement C3)
T4N (p.Thr4Asn) in C3 (Complement C3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
T4N (p.Thr4Asn) variant details
- p.Thr4Asn
- gnomAD rs1400705088
- Missense
- Variant Prioritization Score for Impact Estimate 0.191
- REVEL 0.15
- CADD 5.71
- PolyPhen-2 0.00
- SIFT 0.11
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available