T140P (p.Thr140Pro) variant of C3 (Complement C3)
T140P (p.Thr140Pro) in C3 (Complement C3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.71 / 1. The record also includes population frequency data and structural context.
T140P (p.Thr140Pro) variant details
- p.Thr140Pro
- Ensembl rs1599528602
- Missense
- Variant Prioritization Score for Impact Estimate 0.71
- REVEL 0.74
- CADD 29.30
- PolyPhen-2 0.99
- SIFT 0.00
- Population evidence available
- Structural context available