S23T (p.Ser23Thr) variant of C3 (Complement C3)
S23T (p.Ser23Thr) in C3 (Complement C3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
S23T (p.Ser23Thr) variant details
- p.Ser23Thr
- Ensembl rs771249936
- Missense
- Variant Prioritization Score for Impact Estimate 0.131
- REVEL 0.18
- CADD 1.81
- PolyPhen-2 0.00
- SIFT 0.31
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available