S23R (p.Ser23Arg) variant of C3 (Complement C3)
S23R (p.Ser23Arg) in C3 (Complement C3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
S23R (p.Ser23Arg) variant details
- p.Ser23Arg
- gnomAD rs1445790122
- Missense
- Variant Prioritization Score for Impact Estimate 0.105
- REVEL 0.13
- CADD 1.12
- PolyPhen-2 0.01
- SIFT 0.29
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available