S23I (p.Ser23Ile) variant of C3 (Complement C3)
S23I (p.Ser23Ile) in C3 (Complement C3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
S23I (p.Ser23Ile) variant details
- p.Ser23Ile
- Ensembl rs771249936
- Missense
- Variant Prioritization Score for Impact Estimate 0.131
- REVEL 0.16
- CADD 5.70
- PolyPhen-2 0.00
- SIFT 0.12
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available