P3S (p.Pro3Ser) variant of C3 (Complement C3)
P3S (p.Pro3Ser) in C3 (Complement C3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
P3S (p.Pro3Ser) variant details
- p.Pro3Ser
- ExAC rs757609303
- TOPMed rs757609303
- gnomAD rs757609303
- Missense
- Variant Prioritization Score for Impact Estimate 0.15
- REVEL 0.10
- CADD 9.98
- PolyPhen-2 0.13
- SIFT 0.07
- Most common in the East Asian population (allele frequency 0.00058)
- Structural context available