N81D (p.Asn81Asp) variant of C3 (Complement C3)
N81D (p.Asn81Asp) in C3 (Complement C3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
N81D (p.Asn81Asp) variant details
- p.Asn81Asp
- ExAC rs767630028
- TOPMed rs767630028
- gnomAD rs767630028
- Missense
- Variant Prioritization Score for Impact Estimate 0.189
- REVEL 0.19
- CADD 2.54
- PolyPhen-2 0.00
- SIFT 0.11
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available