M83T (p.Met83Thr) variant of C3 (Complement C3)
M83T (p.Met83Thr) in C3 (Complement C3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
M83T (p.Met83Thr) variant details
- p.Met83Thr
- gnomAD rs1332648857
- Missense
- Variant Prioritization Score for Impact Estimate 0.402
- REVEL 0.30
- CADD 18.40
- PolyPhen-2 0.01
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available