I167M (p.Ile167Met) variant of C3 (Complement C3)
I167M (p.Ile167Met) in C3 (Complement C3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
I167M (p.Ile167Met) variant details
- p.Ile167Met
- TOPMed rs1330765911
- gnomAD rs1330765911
- Missense
- Variant Prioritization Score for Impact Estimate 0.408
- REVEL 0.57
- CADD 16.30
- PolyPhen-2 0.89
- SIFT 0.02
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available