G128R (p.Gly128Arg) variant of C3 (Complement C3)
G128R (p.Gly128Arg) in C3 (Complement C3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.67 / 1. The record also includes population frequency data and structural context.
G128R (p.Gly128Arg) variant details
- p.Gly128Arg
- TOPMed rs1968086495
- Missense
- Variant Prioritization Score for Impact Estimate 0.669
- REVEL 0.59
- CADD 25.50
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available