L24F (p.Leu24Phe) variant of C2CD2L (O14523)
L24F (p.Leu24Phe) in C2CD2L (O14523) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
L24F (p.Leu24Phe) variant details
- p.Leu24Phe
- gnomAD rs1280335043
- Missense
- Variant Prioritization Score for Impact Estimate 0.192
- REVEL 0.06
- ESM-1b 0.00
- AlphaMissense 0.12
- CADD 22.90
- PolyPhen-2 0.56
- SIFT 0.07
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available