S25T (p.Ser25Thr) variant of BUB1B (O60566)
S25T (p.Ser25Thr) in BUB1B (O60566) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data, published literature, and structural context.
S25T (p.Ser25Thr) variant details
- p.Ser25Thr
- gnomAD 15-40165091-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.408
- REVEL 0.20
- CADD 26.30
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available