L11V (p.Leu11Val) variant of BTK (Tyrosine-protein kinase BTK)
L11V (p.Leu11Val) in BTK (Tyrosine-protein kinase BTK) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact in the context of in XLA. The record also includes experimental measurements and structural context.
L11V (p.Leu11Val) variant details
- p.Leu11Val
- NCI-TCGA Cosmic COSV5812
- cosmic curated COSV58120
- Variant assessed as somatic; moderate impact.
- in XLA
- Missense
- UniProt: Variant assessed as somatic; moderate impact. (in XLA)
- Structural context available
- BTK SH3 domain domainome 1.0: score 0.0169