W120C (p.Trp120Cys) variant of BRD4 (Bromodomain-containing protein 4)
W120C (p.Trp120Cys) in BRD4 (Bromodomain-containing protein 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data and structural context.
W120C (p.Trp120Cys) variant details
- p.Trp120Cys
- cosmic curated COSV54585
- ExAC rs748114590
- Missense
- Variant Prioritization Score for Impact Estimate 0.636
- MetaLR 0.15
- MetaSVM -0.94
- CADD 29.40
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available