T23N (p.Thr23Asn) variant of BRD4 (Bromodomain-containing protein 4)
T23N (p.Thr23Asn) in BRD4 (Bromodomain-containing protein 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data, experimental measurements, and structural context.
T23N (p.Thr23Asn) variant details
- p.Thr23Asn
- ExAC rs777108318
- gnomAD rs777108318
- Missense
- Variant Prioritization Score for Impact Estimate 0.546
- MetaLR 0.06
- MetaSVM -1.01
- CADD 22.40
- PolyPhen-2 0.19
- SIFT 0.09
- Most common in the Non-Finnish European population (allele frequency 4.5e-06)
- Structural context available
- BRD4 NET domain domainome 1.0: score 0.195