R10I (p.Arg10Ile) variant of BRD4 (Bromodomain-containing protein 4)
R10I (p.Arg10Ile) in BRD4 (Bromodomain-containing protein 4) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The record also includes variant effect predictions, experimental measurements, and structural context.
R10I (p.Arg10Ile) variant details
- p.Arg10Ile
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- MetaLR 0.24
- MetaSVM -0.64
- SIFT 0.00
- UniProt: Variant assessed as somatic; moderate impact.
- Structural context available
- BRD4 NET domain domainome 1.0: score -0.511