Q64R (p.Gln64Arg) variant of BRD4 (Bromodomain-containing protein 4)
Q64R (p.Gln64Arg) in BRD4 (Bromodomain-containing protein 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data, experimental measurements, and structural context.
Q64R (p.Gln64Arg) variant details
- p.Gln64Arg
- Ensembl rs2047604486
- Missense
- Variant Prioritization Score for Impact Estimate 0.501
- MetaLR 0.13
- MetaSVM -0.95
- CADD 26.20
- PolyPhen-2 0.95
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available
- BRD4 NET domain domainome 1.0: score -0.571