Q25R (p.Gln25Arg) variant of BRD4 (Bromodomain-containing protein 4)
Q25R (p.Gln25Arg) in BRD4 (Bromodomain-containing protein 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data, experimental measurements, and structural context.
Q25R (p.Gln25Arg) variant details
- p.Gln25Arg
- gnomAD rs2047606477
- Missense
- Variant Prioritization Score for Impact Estimate 0.433
- MetaLR 0.15
- MetaSVM -0.97
- CADD 25.90
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available
- BRD4 NET domain domainome 1.0: score -0.346