P47T (p.Pro47Thr) variant of BRD4 (Bromodomain-containing protein 4)
P47T (p.Pro47Thr) in BRD4 (Bromodomain-containing protein 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data, experimental measurements, and structural context.
P47T (p.Pro47Thr) variant details
- p.Pro47Thr
- gnomAD rs1301560534
- Missense
- Variant Prioritization Score for Impact Estimate 0.575
- MetaLR 0.14
- MetaSVM -0.97
- CADD 24.60
- SIFT 0.04
- Most common in the Finnish in Finland (FIN) population (allele frequency 9.4e-05)
- Structural context available
- BRD4 NET domain domainome 1.0: score -0.718