P35A (p.Pro35Ala) variant of BRD4 (Bromodomain-containing protein 4)
P35A (p.Pro35Ala) in BRD4 (Bromodomain-containing protein 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data, experimental measurements, and structural context.
P35A (p.Pro35Ala) variant details
- p.Pro35Ala
- gnomAD rs2047605830
- Missense
- Variant Prioritization Score for Impact Estimate 0.546
- MetaLR 0.08
- MetaSVM -1.09
- CADD 20.70
- SIFT 0.12
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available
- BRD4 NET domain domainome 1.0: score -0.368