P15S (p.Pro15Ser) variant of BRD4 (Bromodomain-containing protein 4)
P15S (p.Pro15Ser) in BRD4 (Bromodomain-containing protein 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data, experimental measurements, and structural context.
P15S (p.Pro15Ser) variant details
- p.Pro15Ser
- gnomAD rs2047606919
- Missense
- Variant Prioritization Score for Impact Estimate 0.537
- MetaLR 0.02
- MetaSVM -0.98
- CADD 21.90
- PolyPhen-2 0.06
- SIFT 0.21
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available
- BRD4 NET domain domainome 1.0: score -0.0498