N39S (p.Asn39Ser) variant of BRD4 (Bromodomain-containing protein 4)
N39S (p.Asn39Ser) in BRD4 (Bromodomain-containing protein 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data, experimental measurements, and structural context.
N39S (p.Asn39Ser) variant details
- p.Asn39Ser
- TOPMed rs2047605708
- Missense
- Variant Prioritization Score for Impact Estimate 0.204
- MetaLR 0.03
- MetaSVM -0.99
- CADD 8.25
- PolyPhen-2 0.00
- SIFT 0.90
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- BRD4 NET domain domainome 1.0: score -0.251