K99N (p.Lys99Asn) variant of BRD4 (Bromodomain-containing protein 4)
K99N (p.Lys99Asn) in BRD4 (Bromodomain-containing protein 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
K99N (p.Lys99Asn) variant details
- p.Lys99Asn
- ExAC rs763461840
- TOPMed rs763461840
- gnomAD rs763461840
- Missense
- Variant Prioritization Score for Impact Estimate 0.429
- MetaLR 0.08
- MetaSVM -1.08
- CADD 21.30
- PolyPhen-2 0.80
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 7.2e-05)
- Structural context available