K91R (p.Lys91Arg) variant of BRD4 (Bromodomain-containing protein 4)
K91R (p.Lys91Arg) in BRD4 (Bromodomain-containing protein 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
K91R (p.Lys91Arg) variant details
- p.Lys91Arg
- 1000Genomes rs559089423
- ExAC rs559089423
- gnomAD rs559089423
- Missense
- Variant Prioritization Score for Impact Estimate 0.503
- MetaLR 0.12
- MetaSVM -1.02
- CADD 27.60
- PolyPhen-2 0.92
- SIFT 0.00
- Most common in the 1KG:ASW population (allele frequency 0.0098)
- Structural context available