K72R (p.Lys72Arg) variant of BRD4 (Bromodomain-containing protein 4)
K72R (p.Lys72Arg) in BRD4 (Bromodomain-containing protein 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
K72R (p.Lys72Arg) variant details
- p.Lys72Arg
- cosmic curated COSV54585
- TOPMed rs1173805182
- gnomAD rs1173805182
- Missense
- Variant Prioritization Score for Impact Estimate 0.441
- MetaLR 0.11
- MetaSVM -0.98
- CADD 26.90
- PolyPhen-2 0.99
- SIFT 0.07
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available