K112T (p.Lys112Thr) variant of BRD4 (Bromodomain-containing protein 4)
K112T (p.Lys112Thr) in BRD4 (Bromodomain-containing protein 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data and structural context.
K112T (p.Lys112Thr) variant details
- p.Lys112Thr
- TOPMed rs199654568
- gnomAD rs199654568
- Missense
- Variant Prioritization Score for Impact Estimate 0.533
- MetaLR 0.21
- MetaSVM -0.68
- CADD 26.60
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available