K112R (p.Lys112Arg) variant of BRD4 (Bromodomain-containing protein 4)
K112R (p.Lys112Arg) in BRD4 (Bromodomain-containing protein 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
K112R (p.Lys112Arg) variant details
- p.Lys112Arg
- TOPMed rs199654568
- gnomAD rs199654568
- Missense
- Variant Prioritization Score for Impact Estimate 0.514
- MetaLR 0.16
- MetaSVM -0.91
- CADD 24.40
- PolyPhen-2 0.89
- SIFT 0.12
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available