G20R (p.Gly20Arg) variant of BRD4 (Bromodomain-containing protein 4)
G20R (p.Gly20Arg) in BRD4 (Bromodomain-containing protein 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data, experimental measurements, and structural context.
G20R (p.Gly20Arg) variant details
- p.Gly20Arg
- Ensembl rs527856622
- Missense
- Variant Prioritization Score for Impact Estimate 0.59
- MetaLR 0.17
- MetaSVM -0.80
- CADD 25.80
- SIFT 0.00
- Most common in the HGDP:SURUI population (allele frequency 0.5)
- Structural context available
- BRD4 NET domain domainome 1.0: score -0.256