E4* (p.Glu4Ter) variant of BRD4 (Bromodomain-containing protein 4)
E4* (p.Glu4Ter) in BRD4 (Bromodomain-containing protein 4) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.81 / 1. The record also includes population frequency data, experimental measurements, and structural context.
E4* (p.Glu4Ter) variant details
- p.Glu4Ter
- gnomAD rs2047607504
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.813
- CADD 36.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available
- BRD4 NET domain domainome 1.0: score -0.805