D19G (p.Asp19Gly) variant of BRD4 (Bromodomain-containing protein 4)
D19G (p.Asp19Gly) in BRD4 (Bromodomain-containing protein 4) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The record also includes variant effect predictions, experimental measurements, and structural context.
D19G (p.Asp19Gly) variant details
- p.Asp19Gly
- NCI-TCGA Cosmic COSV9965
- cosmic curated COSV99650
- Ensembl rs2145625424
- Variant assessed as somatic; moderate impact.
- Missense
- MetaLR 0.17
- MetaSVM -0.83
- SIFT 0.00
- UniProt: Variant assessed as somatic; moderate impact.
- Structural context available
- BRD4 NET domain domainome 1.0: score -0.656