A41T (p.Ala41Thr) variant of BRD4 (Bromodomain-containing protein 4)
A41T (p.Ala41Thr) in BRD4 (Bromodomain-containing protein 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data, experimental measurements, and structural context.
A41T (p.Ala41Thr) variant details
- p.Ala41Thr
- Ensembl rs2145625050
- Missense
- Variant Prioritization Score for Impact Estimate 0.47
- MetaLR 0.05
- MetaSVM -1.06
- CADD 20.60
- PolyPhen-2 0.04
- SIFT 0.19
- Most common in the East Asian population (allele frequency 7.6e-05)
- Structural context available
- BRD4 NET domain domainome 1.0: score 0.104