A38D (p.Ala38Asp) variant of BRD4 (Bromodomain-containing protein 4)
A38D (p.Ala38Asp) in BRD4 (Bromodomain-containing protein 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data, experimental measurements, and structural context.
A38D (p.Ala38Asp) variant details
- p.Ala38Asp
- Ensembl rs2047605745
- Missense
- Variant Prioritization Score for Impact Estimate 0.469
- MetaLR 0.03
- MetaSVM -1.08
- CADD 22.00
- PolyPhen-2 0.03
- SIFT 0.01
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available
- BRD4 NET domain domainome 1.0: score 0.0325