V5A (p.Val5Ala) variant of BRD2 (Bromodomain-containing protein 2)
V5A (p.Val5Ala) in BRD2 (Bromodomain-containing protein 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
V5A (p.Val5Ala) variant details
- p.Val5Ala
- ExAC rs765229853
- TOPMed rs765229853
- gnomAD rs765229853
- Missense
- Variant Prioritization Score for Impact Estimate 0.33
- REVEL 0.12
- CADD 25.70
- PolyPhen-2 0.15
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 7.2e-05)
- Structural context available