T6I (p.Thr6Ile) variant of BRD2 (Bromodomain-containing protein 2)
T6I (p.Thr6Ile) in BRD2 (Bromodomain-containing protein 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
T6I (p.Thr6Ile) variant details
- p.Thr6Ile
- ExAC rs777834793
- TOPMed rs777834793
- gnomAD rs777834793
- Missense
- Variant Prioritization Score for Impact Estimate 0.412
- REVEL 0.16
- CADD 24.30
- PolyPhen-2 0.51
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available