T6A (p.Thr6Ala) variant of BRD2 (Bromodomain-containing protein 2)
T6A (p.Thr6Ala) in BRD2 (Bromodomain-containing protein 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
T6A (p.Thr6Ala) variant details
- p.Thr6Ala
- ExAC rs758704519
- TOPMed rs758704519
- gnomAD rs758704519
- Missense
- Variant Prioritization Score for Impact Estimate 0.235
- REVEL 0.14
- CADD 23.40
- PolyPhen-2 0.22
- SIFT 0.07
- Most common in the HGDP:BANTUSOUTHAFRICA population (allele frequency 0.062)
- Structural context available