S45R (p.Ser45Arg) variant of BRD2 (Bromodomain-containing protein 2)
S45R (p.Ser45Arg) in BRD2 (Bromodomain-containing protein 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
S45R (p.Ser45Arg) variant details
- p.Ser45Arg
- ExAC rs747061505
- TOPMed rs747061505
- gnomAD rs747061505
- Missense
- Variant Prioritization Score for Impact Estimate 0.23
- REVEL 0.12
- CADD 24.20
- PolyPhen-2 0.35
- SIFT 0.01
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available